User:Raesh/Buff Guide

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This is a guide for what buffs you should be using throughout the game for boss fights, and when upgrades become available. Certain buffs have conditions the player should consider, such as negative effects, being based on what gear the player is using, or varying in effectiveness based on the boss.

Universal Vanilla Buffs

Item Avaliability Conditions
Regeneration PotionRegeneration Potion
Ironskin PotionIronskin Potion
Swiftness PotionSwiftness Potion
Endurance PotionEndurance Potion
Wrath PotionWrath Potion
Rage PotionRage Potion Summons cannot crit
Heartreach PotionHeartreach Potion Against bosses with servants[1] or while using Heart Statues, Bloodflare armor, or Rare Elemental in a Bottle. Has no effect when used with Tarragon armor or Auric Tesla armor
Inferno PotionInferno Potion Especially effective against bosses with servants [1] or breakable projectiles[2]
Exquisitely StuffedExquisitely Stuffed
Warmth PotionWarmth Potion Against Deerclops, Cryogen, Anahita, Ravager, Lunatic Cultist, and Storm Weaver
Titan PotionTitan Potion Against bosses with servants[1]
Water Walking PotionWater Walking Potion Against bosses in the Underworld when not using Terraspark Boots
Obsidian Skin PotionObsidian Skin Potion Against all 3 Mechanical Bosses, Golem, Ravager, Lunatic Cultist, and the Exo Mechs if you do not already have immunity to On Fire!
Flipper PotionFlipper Potion When using an arena with Honey
Slice of CakeSlice of Cake Party Girl
Lifeforce PotionLifeforce Potion Hardmode, Shadow Chests, Abyssal Treasure, Sulphuric Treasure, or Arsenal Labs

Universal Calamity Buffs

Item Availability Conditions
Bounding PotionBounding Potion
Potion of OmnisciencePotion of Omniscience
BaguetteBaguette When using Red Wine
Tesla PotionTesla Potion Post-Hive Mind/Perforators Especially effective against Storm Weaver, and bosses with servants[1] or breakable projectiles[2]
Photosynthesis PotionPhotosynthesis Potion Hardmode
Soaring PotionSoaring Potion Hardmode
Odd MushroomOdd Mushroom Hardmode Gain 50% damage in exchange for greatly reduced visibility
Gravity Normalizer PotionGravity Normalizer Potion Post-Astrum Aureus Against Ceaseless Void or when near Space
  1. 1.0 1.1 1.2 1.3 Boss servants include Calamity Boss Servants and Vanilla Boss Servants
  2. 2.0 2.1 Bosses with breakable projectiles include Plantera's Spores, Duke Fishron's Bubbles, Lunatic Cultist's Ancient Light, and Eater of Worlds's Vile spit

Arena Buffs

Buffs Availability Conditions
CampfireCampfire
Heart LanternHeart Lantern
Bast StatueBast Statue
SunflowerSunflower Requires solid grass blocks
Star in a BottleStar in a Bottle When using weapons that require mana
HoneyHoney Use with Flipper Potion and Bubble
Corruption EffigyCorruption Effigy Corruption Shrine Lose 5% DR for 10% crit and movement speed
Crimson EffigyCrimson Effigy Crimson Shrine Lose 10% HP for 15% damage and 10 defense
Weightless CandleWeightless Candle Hardmode
Vigorous CandleVigorous Candle Hardmode
Resilient CandleResilient Candle Hardmode
Spiteful CandleSpiteful Candle Hardmode

Class Specific Buffs

Melee

Buffs Availability Conditions
Sharpening StationSharpening Station
AleAle
SakeSake
Lose 5% defense for 10% damage
Flask of PoisonFlask of Poison
Flask of FireFlask of Fire
Post-Queen Bee Poison vs Fire will depend on the boss[1]
Flask of CrumblingFlask of Crumbling
Flask of IchorFlask of Ichor
Hardmode Ichor vs Crumbling will depend on the boss[2]

Ranger

Buffs Conditions
Archery PotionArchery Potion When using weapons that fire arrows
Ammo Reservation PotionAmmo Reservation Potion
Ammo BoxAmmo Box

Mage

Buffs Availability Conditions
Magic Power PotionMagic Power Potion
Mana Regeneration PotionMana Regeneration Potion
Crystal BallCrystal Ball Hardmode
White WineWhite Wine Post-All Mechanical Bosses Lose 6% defense and 1 life regen for 8% damage
Star Beam RyeStar Beam Rye Post-Astrum Aureus Lose 6% defense and 2 life regen for 8% damage, 10% reduced mana usage, and 50 increased mana
Aureus CellAureus Cell Post-Astrum Aureus Can be used instead of Magic Power Potion and Mana Regeneration Potion

Summoner

Buffs Availability Conditions
Summoning PotionSummoning Potion
War TableWar Table Post-Eater of Worlds/Brain of Cthulhu
Bewitching TableBewitching Table Post-Skeletron
Flask of PoisonFlask of Poison
Flask of FireFlask of Fire
Post-Queen Bee Poison vs Fire will depend on the boss[1]
Flask of CrumblingFlask of Crumbling
Flask of IchorFlask of Ichor
Hardmode Ichor vs Crumbling will depend on the boss[2]

Rogue

Buffs Availability Conditions
Shadow PotionShadow Potion
Flask of PoisonFlask of Poison
Flask of FireFlask of Fire
Post-Queen Bee Poison vs Fire will depend on the boss[1]
Flask of CrumblingFlask of Crumbling
Flask of IchorFlask of Ichor
Hardmode Ichor vs Crumbling will depend on the boss[2]
  1. 1.0 1.1 1.2 Flask of Poison is better for Deerclops, and Wall of Flesh, while Flask of Fire is better for Skeletron and Slime God.
  2. 2.0 2.1 2.2 Crumbling will only be better if you are using a weapon that does very high damage hits, against an enemy with at least 20-25% DR. If the enemy has both defense and DR, and you already have a way to reduce one, use the flask for whatever stat you are not already reducing.

Alcohol

Having more than 3 alcohol buffs at a time will make you take damage over time, as such it is only recommended to use up to 3 of the following. Note that White Wine, Star Beam Rye, and Ale/Sake mentioned in the class buffs section are also alcohol, and will count towards your limit of 3.

Buffs Availability Conditions
WhiskeyWhiskey Hardmode Lose 5% defense for 4% damage and 2% crit
RumRum Hardmode Lose 5% defense for 2 life regen and 10% movement speed
TequilaTequila Hardmode Only usable during day. Lose 1 life regen for 4% crit and 5 defense
FireballFireball Hardmode Only usable with Heat Debuffs. Lose 1 life regen for 25% heat debuff damage
Fabsol's VodkaFabsol's Vodka Hardmode Lose 10% defense for 8% damage and 10 immunity frames
VodkaVodka Post-All Mechanical Bosses Lose 5% defense and 1 life regen for 6% damage and 2% crit
ScrewdriverScrewdriver Post-All Mechanical Bosses Only usable with piercing weapons. Lose 1 life regen for 5% damage
Evergreen GinEvergreen Gin Post-Plantera Only usable with Sickness Debuffs/Water Debuffs. Lose 1 life regen for 25% sickness/water debuff damage
Caribbean RumCaribbean Rum Post-Plantera Lose 10% defense for 2 life regen, 10% movement speed, and 20% flight time
MargaritaMargarita Post-Plantera Lose 6% defense and 1 life regen but halves all debuff durations. Strictly worse than other healing potions, but can be taken prefight for the buff only, giving a functional duration of 2 minutes
Old FashionedOld Fashioned Post-Plantera Multiplies all armor set bonus and accessory damage by 1.5x, but reduces all damage by 25%
EverclearEverclear Post-Astrum Aureus Lose 30% defense and 10 life regen for 25% damage (This takes up 2/3 spots for the alcohol limit)
Bloody MaryBloody Mary Post-Astrum Aureus Only usable during blood moon. Lose 4% defense and 4 life regen for 10% damage and movement speed
MoonshineMoonshine Post-Golem Lose 1 life regen for 10 defense and 3% damage reduction
Moscow MuleMoscow Mule Post-Golem Lose 4 life regen for 9% damage and 3% crit
Cinnamon RollCinnamon Roll Post-Golem Only usable with heat debuffs. Lose 10% defense for 50% heat debuff damage
Tequila SunriseTequila Sunrise Post-Golem Only usable during day. Lose 2 life regen for 8% crit and 10 defense

Healing

Buffs Availability Conditions
Healing PotionHealing Potion
Bottled HoneyBottled Honey Heals more than a Healing Potion over time
HoneyfinHoneyfin
Restoration PotionRestoration Potion
Better than a Healing Potion, but can be tedious to obtain
Hadal StewHadal Stew Best Pre-Hardmode healing option, but are tedious to obtain
Greater Healing PotionGreater Healing Potion Hardmode
Red WineRed Wine Hardmode Despite reduced life regen, is still better than Super Healing Potions when used alongside Baguette
Super Healing PotionSuper Healing Potion Post-Lunatic Cultist
Supreme Healing PotionSupreme Healing Potion Post-Providence
BloodfinBloodfin Post-Providence Heals more than a Supreme Healing Potion over time
Omega Healing PotionOmega Healing Potion Post-Devourer of Gods